Advancing implementation of eHealth interventions for HIV prevention through the scale up of Keep It Up!

Brian Mustanski, PhD
Northwestern University

Nanette Benbow, M.A.S.
Northwestern University

Kathryn Macapagal, PhD
Northwestern University

Dennis Li, PhD, MPH
Northwestern University

ABSTRACT:
Despite substantial NIH investment in developing eHealth HIV prevention interventions, little implementation research has examined strategies to effectively scale up these programs. The Keep It Up! 3.0 study advances our knowledge by comparing two approaches for delivering an online CDC-best-evidence HIV intervention in 44 counties. This presentation describes our county-randomized hybrid type III effectiveness–implementation trial, focusing on the pragmatic design of our sampling methodology, outcome measures, the intervention application, and recruitment/retention protocols. By emulating real-world contexts, we can understand how to not only have the greatest public health impact with but also speed up implementation of eHealth HIV interventions.