A tailored clinic-level intervention using a stepped-wedge design to increase PrEP uptake in primary care settings

Parya Saberi, PharmD, MAS, AAHIVP
University of California, San Francisco

Wayne Steward, PhD, MPH
University of California, San Francisco

ABSTRACT:
Lack of healthcare provider knowledge, capacity, and willingness to prescribe PrEP are barriers to PrEP delivery in clinical settings. In this presentation, we will discuss details of the PrEP Optimization Intervention (PrEP-OI) which combines a PrEP Coordinator with an online panel management tool to assist providers with PrEP uptake, persistence, and management in a large safety-net system. The intervention was rolled out at 12 primary care San Francisco Department of Public Health clinics using a stepped-wedge design preceding a follow-up phase. Additionally, we will review the challenges the study overcame with the development of PrEP-OI's technology-based component, onboarding and implementation, and response to the SARS-CoV-2 pandemic.