Project MIMIC (Maximizing Implementation of Motivational Incentives in Clinics): A type 3 effectiveness-implementation hybrid trial

Bryan Garner, Ph.D.
Research Triangle Institute (RTI)

Sara Becker, Ph.D.
Department for Behavioral and Social Sciences, Brown University School of Public Health

ABSTRACT:
There is an urgent public health need to improve the outcomes of individuals with opioid use disorders (OUDs). There are currently five approved medication formulations, which relative to placebo have demonstrated effectiveness in helping patients attain abstinence from opioids. Nonetheless, patients’ opioid abstinence rates are sub-optimal: even when treated with the newest extended-release formulations only about 40% of patients maintain abstinence during the first 6-months of treatment. Contingency Management (CM) is one of the only behavioral treatment shown to improve OUD pharmacotherapy outcomes, yet implementation of CM within OUD treatment centers remains quite low. Project MIMIC is a type 3 effectiveness-implementation hybrid trial to test the effectiveness of an enhanced-version of the Addiction Technology Transfer Center’s current multifaceted implementation strategy on both implementation outcomes (primary aim) and patient outcomes (secondary aim). For this PSMG web-presentation, Drs. Becker and Garner (Project MIMIC’s principal investigators) will teach others about the project and its protocol, with special emphasis on helping the audience learn more about the project’s two implementation conditions, key challenges, and key lessons learned.